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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Synergy of nanodiamond–doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cells

Fig. 10

PD-L1 blockade potentiated Nano-DOX’s therapeutic efficacy against subcutaneous grafts of Lewis cells. A, B Growth curves of Lewis tumor xenografts with or without TAM depletion. Growth rates over the treatment duration (from day 13 to day 27) were calculated by regression analysis. C Tumor growth over the treatment duration, which is expressed as tumor volume on the last day as the percentage of tumor volume on the first day in a mouse. D Tumor weight at the time of sacrifice. E Dissected tumor grafts after sacrifice. Values were means ± SD (n = 3, *p < 0.05)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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