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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury

Fig. 2

CD73+ ucMSC-EVs promote M2 polarization and inhibit M1 polarization in vitro. A The effects of 30 ng/ml CD73, 30 μg/ml hucMSC-EVs and 30 μg/ml CD73+hucMSC-EVs with or without 100 μM APCP on the change of M1 subsets in BV2 cells treated with 1 μg/ml LPS are determined by immunofluorescences. B The effects of 30 ng/ml CD73, 30 μg/ml hucMSC-EVs and 30 μg/ml CD73+ hucMSC-EVs with or without 100 μM APCP on the change of M2 subsets in BV2 cells treated with 5 μg/ml IL-4 are determined by immunofluorescences. C and D Fluorescent intensities are normalized to fluorescent levels in LPS group or IL-4 group (*p < 0.05 versus LPS/IL-4, #p < 0.05 versus LPS/IL-4 + CD73+hucMSC-EVs, n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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