Fig. 6From: Atovaquone-HSA nano-drugs enhance the efficacy of PD-1 blockade immunotherapy by alleviating hypoxic tumor microenvironment Relief of immunosuppressive tumor immune microenvironment by HSA-ATO NPs. a Flow cytometry analysis of CD4+/CD8+ cells in tumors from mice with the indicated treatments. The quantity of immune cells (b) and the content of Granzyme (c) and IFN-γ (d) in xenograft tumors from mice with the indicated treatments were analyzed by immunofluorescence and ELISA assays. Data are presented as mean ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.001Back to article page