Fig. 8From: Intrinsic nucleus-targeted ultra-small metal–organic framework for the type I sonodynamic treatment of orthotopic pancreatic carcinomaIn vivo antitumor evaluation. a Schematic illustration of the therapy process. b Fluorescence images of tumor-bearing mice after various treatments. c Tumor fluorescence intensity changes and d survival rates of tumor-bearing mice after different treatments. Data are means ± SD (n = 5). e H&E, TUNEL, Ki67, and γ-H2AX staining of tumors 15 day after various treatments (Scale bar = 100 µm)Back to article page