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Table 2 The viscera index of mice treated with different formulations

From: A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer

Groups

Heart index (%)

Liver index (%)

Lung index (%)

Kidney index (%)

Saline

0.79 ± 0.07

7.47 ± 1.36

0.80 ± 0.13

2.30 ± 0.34

FA-PEG-CM-β-CD

0.78 ± 0.06

7.57 ± 1.12

0.82 ± 0.26

2.30 ± 0.36

5-ASA

0.80 ± 0.11

7.49 ± 0.88

0.83 ± 0.16

2.35 ± 0.33

NaB

0.83 ± 0.12

7.61 ± 1.33

0.84 ± 0.31

2.31 ± 0.26

BBA

0.87 ± 0.08

7.05 ± 0.58

0.80 ± 0.21

2.55 ± 0.62

5-FU

0.81 ± 0.28

8.34 ± 0.43*

0.85 ± 0.11

3.06 ± 0.27**

BBA/CM-β-CD

0.80 ± 0.26

7.17 ± 0.63

0.79 ± 0.25

2.17 ± 0.37

FA-PEG-CM-β-CD

0.78 ± 0.06

7.57 ± 1.11

0.82 ± 0.26

2.30 ± 0.36

BBA/FA-PEG-CM-β-CD

0.80 ± 0.11

7.29 ± 0.71

0.81 ± 0.23

2.36 ± 0.24

  1. Results were presented as mean ± S D (n = 5). Symbols represented statistical significance compared with Saline group. *P < 0.05, **P < 0.01