Fig. 4

Surgical implantation and outcome of cellularized tubular HA/collagen nanofibrous scaffold graft. An end-to-end anastomosis procedure with the nanofibrous scaffold graft sutured to the carotid artery in rabbit (a). A representative angiography image shows absence of aneurysm along the entire length of the graft (b). A summary of ultrasound measurements revealed a stable lumen caliber for the duration of the 6 weeks study. Black arrows show margins of tissue-engineered blood vessel. Scale bars, a, b 1 cm, c tensile strength was compared between pre-implant nanofibrous scaffold strips, 6 weeks retrieved explant strips and carotid artery strips (n = 3). *p \(<\) 0.05