Biomimetic 2D layered double hydroxide nanocomposites for hyperthermia-facilitated homologous targeting cancer photo-chemotherapy

Table 1 Size, PDI, zeta potential, loading efficiency, and capacity of LDH-based NSs

Sample	Size (d. nm)	PDI	Zeta potential (mV)	Loading efficiency of ICG/PTX-BSA (%)^c	Loading capacity of ICG/PTX-BSA (%)^c
LDH	76.3 ± 3.6	0.324	34.6 ± 6.4	−/−	−/−
LI	77.6 ± 2.8	0.246	38.7 ± 1.0	61.8 ± 1.2/–	4.7 ± 0.1/−
LIP^a	104.2 ± 5.5	0.265	− 16.1 ± 1.6	61.7 ± 0.2/99.9 ± 0.1	4.6 ± 0.1/2.3 ± 0.1
LIPC^a,b	116.3 ± 4.5	0.217	− 19.2 ± 2.7	61.7 ± 0.1/99.9 ± 0.1	4.6 ± 0.1/2.3 ± 0.1

^aBSA was employed for coating LIP and LIPC but was not calculated in loading capacity
^bThe loading efficiency and capacity of CCM on LIPC were 98.6% and 4.7%, respectively at the mass ratio of LDH to CCM of 20:1
^cLoading efficiency (wt%) = Mass of ICG/PTX-BSA in NSs/Mass of ICG/PTX-BSA added × 100%; Loading capacity (wt%) = Mass of ICG/PTX-BSA in NSs/Mass of NSs × 100%

ISSN: 1477-3155