Fig. 12

In vivo safety assessment and Histological examination analysis. A–C AST, ALT, CRE, and BUN from the blood samples isolated from orthotopic glioma tumor tissues after treatment with saline, taxol, PTX/PMs, and PTX/Aβ-CN-PMs, respectively, Means ± SD, n = 6; *P < 0.05, **P < 0.01, ***P < 0.001 versus the PTX/Aβ-CN-PMs group. D The rate of change in body weight of orthotopic glioma tumor mice in the different groups at different time points (n = 6). E Kaplan–Meier survival curves of percentage survival of orthotopic glioma mice treated with saline, taxol, PTX/PMs, and PTX/Aβ-CN-PMs, respectively (n = 10). F H&E staining of hearts, livers, spleens, lungs and kidneys after treatment with saline, taxol, PTX/PMs, and PTX/Aβ-CN-PMs observed by optical microscope (magnification × 100). Scale bar = 200 μm