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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Novel brain-targeted nanomicelles for anti-glioma therapy mediated by the ApoE-enriched protein corona in vivo

Fig. 7

In vitro cellular uptake on HUVEC cells. A CLSM observation of HUVEC cells after treatment with free Cou-6, Cou-6/PMs, Cou-6/Aβ-CN-PMs, rhApoE/Cou-6/Aβ-CN-PMs for 15, 30, 60 and 120 min(magnification × 200), respectively. B, C Quantitative analysis of cellular uptake by flow cytometry after incubation with free Cou-6, Cou-6/PMs, Cou-6/Aβ-CN-PMs, rhApoE/Cou-6/Aβ-CN-PMs for 2 h, respectively. D, E Quantitative analysis of cellular uptake by flow cytometry after incubation with rhApoE/Cou-6/Aβ-CN-PMs for 15, 30, 60 and 120 min. Means ± SD, n = 3; *P < 0.05, **P < 0.01, ***P < 0.001 versus rhApoE/Cou-6/Aβ-CN-PMs group

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Journal of Nanobiotechnology

ISSN: 1477-3155

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