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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Artificial exosomes mediated spatiotemporal-resolved and targeted delivery of epigenetic inhibitors

Fig. 2

Cellular uptake of artificial exosomes and the nanoparticles induced epigenetic regulation. A CLSM analysis of the cellular uptake of EMF. B Live/Dead analysis of LLC cells treated with different formulations; C Apoptosis of LLC cells treated with different formulations; D The quantitative analysis of apoptosis of LLC cells (n = 3); E Western blotting analysis of LLC cells treated with different formulations; F RNA-Seq analysis of EMS treatment; G GO analysis of EMS treatment; H KEGG analysis of EMS treatment. The cell membranes were stained with DiL. EMF, EM/SUC/FITC. The data were represented as Mean ± SD. The statistical significance was calculated via one-way ANOVA with a Tukey post-hoc test. *P < 0.05; ****P < 0.0001

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