Fig. 3

In vivo Imaging based on the Nd-RENPs in the NIR-II region. a, b NIR-II fluorescence images of 4T1-tumor-bearing mice at 1060 and 1340 nm after Nd-RENP administration. c, d TBR and LBR were calculated by the NIR-II fluorescence imaging of mice at 1060 and 1340 nm. TBR = [(mean fluorescence intensity of tumor)-(mean fluorescence intensity of background)]/[(mean fluorescence intensity of normal tissue)-(mean fluorescence intensity of background)]. LBR = [(mean fluorescence intensity of liver)-(mean fluorescence intensity of background)]/[(mean fluorescence intensity of normal tissue)-(mean fluorescence intensity of background)] (n = 3)