Fig. 2
From: Cell-derived extracellular vesicles and membranes for tissue repair
Engineered stem cell therapy. A Scheme illustrating an example of genetic engineering of stem cells. Bone marrow–derived mesenchymal stem cells (BM-MSCs) were primed by transduction-mediated hepatocyte growth factor–expressing MSCs (HGF-eMSCs) for enhanced efficacy of vascular regeneration and cardiac function restoration in myocardial infarction models. Reproduced from [25]. © The Authors, some rights reserved; exclusive licensee AAAS. B Concept of hydrogels tethering interferon-gamma (IFN-γ) and encapsulating MSCs. Reproduced from [26], copyright 2019, with permission from Elsevier