Fig. 5
Destruction effect of sPDMA@ICG NPs with laser irradiation on plaque biofilm. a Photos of plaque biofilms after various processions and b comparison for destructive area analyzed using Image J. c Fluorescence microscopic images of plaque biofilms stained with the Live/Dead staining kit after various processions. In these above experiments, the plaque biofilms were formed by pathogenic bacteria sourced from periodontitis rats. Here, the plaque biofilms were incubated with sPDMA, ICG and sPDMA@ICG NPs for 3 h, and afterwards, the laser irradiation was carried out at 808 nm at 2 W/cm2 for 5 min. **indicates p < 0.01 compared to the control; ## indicates p < 0.01 for comparison between two groups