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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: MCP mediated active targeting calcium phosphate hybrid nanoparticles for the treatment of orthotopic drug-resistant colon cancer

Fig. 5

The inhibitory effect of PSVII@MCP-CaP on HCT116 cell and HCT116/L cell in vitro. A The inhibitory effect of PSVII@MCP-CaP on the proliferation of HCT116 cells. B The inhibitory effect of PSVII@MCP-CaP on the proliferation of HCT116/L cells. C The inhibitory effect of PSVII@MCP-CaP on the clone formation of HCT116 cell. D The inhibitory effect of PSVII@MCP-CaP on the clone formation of HCT116/L cell. E Live/dead cell staining of HCT116 cell. F Semi-quantitative statistical results of the ratio between dead HCT116 cell and live HCT116 cell. G Live/dead cell staining of HCT116/L cell. H Semi-quantitative statistical results of the ratio between dead HCT116/L cell and live HCT116/L cell. I The effect of PSVII@MCP-CaP on the expression of apoptosis-related proteins in HCT116 cell. J Semi-quantitative statistical results of the expression of apoptosis-related proteins in HCT116 cell. K The effect of PSVII@MCP-CaP on the expression of apoptosis-related proteins in HCT116/L cell. L Semi-quantitative statistical results of the expression of apoptosis-related proteins in HCT116/L cell. All data are expressed as mean ± SD (n = 3). **p < 0.01 vs L-OHP; ##p < 0.01 vs control

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