Fig. 8

Inhibition of local tumor growth and tumor metastasis by ICG@PM@NP mediated mild-PTT in 4T1 tumors. A Schematic diagram of 4T1 tumor experimental design. B–F Tumor growth curves of 4T1 tumor-bearing mice after the following treatments (n = 5): 1. Vehicle; 2. Vehicle + Laser; 3. ICG@NP; 4. ICG@NP + Laser; 5. PM@NP; 6. ICG@PM@NP; 7. ICG@PM@NP + Laser. G Weight of collected 4T1 tumors on Day 14 (n = 5). H The number of 4T1 metastatic foci in the lungs of Balb/C mice on Day 26 (n = 5). I The survival rate of 4T1 tumor-bearing mice (n = 5). Statistical analysis was performed via the two-tail Student’s t-test. * p < 0.05; ** p < 0.01; *** p < 0.001