Fig. 3

Tumor therapy with Gel-N-ICG in xenograft mice model. a Maximum temperature profiles of the tumor site of nude mice after injection with different solutions with or without the 808 nm laser irradiation. b Tumor volume curves over 28 days after different treatment. c Representative in vivo IR thermal images of xenograft mice before and after injection with different solutions with a 5-min exposure to the laser irradiation. d Tumor bearing mice weight change, e tumor size at day 28 and f representative ex vivo tumor images from mice in different treatment groups. All data points represent as mean ± SD (n = 5). NS, *, **, and *** indicate no statistical difference, P < 0.05, P < 0.01, and P < 0.001, respectively, as compared with the PBS group