Fig. 4
Anti-inflammatory activity of CSO@PM in vitro. A LPS adsorption capacity of CSO@PM. The initial concentration of LPS was 1 ng mL−1. B LPS adsorption for the PBS, LPS (100 ng mL−1), CSO (50 μg mL−1), and CSO@PM (50 μg mL−1) groups. C Schematic of the co-culture system composed of RAW246.7 cells, LPS, and CSO@PM. D mRNA and E protein expression of IL-1β and IL-6 in RAW264.7 macrophages. The values are shown as mean ± SD (n = 3) and ** indicates P < 0.001 compared with the corresponding control group