Fig. 5

Effects of CSO@PM on the healing of P. aeruginosa-infected wounds. A Photographs of P. aeruginosa-infected wounds under different treatments. The round blue card with a 5 mm diameter indicates initial wound size. B Fractions of the wounds healed by the different treatments on days 5, 7, and 9. The values are shown as mean ± SD (n = 3). C Quantitative analysis of wound area for each group. The values are shown as mean ± SD (n = 3). * P < 0.1 and ** P < 0.001 compared to the control group. D Photographs and E quantitative counts of bacterial colonies formed by P. aeruginosa obtained from wound tissues. The values were shown as mean ± SD (n = 3). * P < 0.1 and ** P < 0.001 compared to the corresponding control group. F H&E staining images of mouse wound tissue from all groups at days 7. Black arrows indicate the length of newly regenerated epidermis. Yellow arrows indicate thickness of granulation tissue. Scale bar: 200 μm. G Neo-epidermis length and H thickness of granulation tissue data. The values are show as mean ± SD (n = 3). * P < 0.1 and ** P < 0.001 compared to the corresponding control group. I Masson images of mouse wound tissue from all groups on day 7. Scale bar: 100 μm