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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Reactive oxygen species (ROS)-responsive nanoprobe for bioimaging and targeting therapy of osteoarthritis

Fig. 3

Inhibiting the action of proinflammatory factors induced by MIA, as well as protecting the chondrocytes after incubation with DEX, TKP@DEX, CAPP@DEX or TKCP@DEX. a Relative mRNA levels of MMP-13, Il-6, MMP-3 and Col2a1 on MIA-stimulated chondrocytes after incubation with DEX, CAPP@DEX, TKP@DEX or TKCP@DEX. b Immunofluorescence images of MIA-stimulated chondrocytes after incubation with DEX, CAPP@DEX, TKP@DEX or TKCP@DEX. c Quantifying the level of MMP-13and IL-6 after treating with DEX, CAPP@DEX, TKP@DEX or TKCP@DEX for 24 h. Scale bar: 200 μm. (n = 3; mean ± SD; *,# indicate p < 0.05; **, ## indicate p < 0.01, ***; ### indicate p < 0.001.)

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