Fig. 4
Plasma Proteomics characterization of the CDS-PMo12@PVPx(x = 0 ~ 1) NPs. a The plasma protein corona formation process of CDS-PMo12@PVPx(x = 0 ~ 1) NPs, and Plasma Proteomics identified by LC–MS/MS. b The number of plasma protein groups identified by LC–MS/MS from the protein corona of the CDS-PMo12@PVPx(x = 0 ~ 1) NPs, standard deviation across three assay replicates are shown as error bar. c CV% for precision evaluation of three assay replicates. Inner boxplots report the 25% (lower hinge), 50%, and 75% quantiles (upper hinge). Whiskers indicate observations outside hinge ± 1.5* interquartile range (IQR). Violin plots capture all data points. d Volcano plot of the correlations between the P-value and fold change (FC), the normalized abundance ratio of CDS-PMo12@PVP1/CDS-PMo12@PVP0 was used for the calculation the FC.(number of parallel = 3, P-values were calculated with Student’s t-test)