Poly (N-vinylpyrrolidone) modification mitigates plasma protein corona formation on phosphomolybdate-based nanoparticles

Table 1 The adsorption kinetics and thermodynamic parameters of the protein/PMo12-based NPs complexes obtained from fluorescence quenching data

Proteins/PMo₁₂ NPs	Temp (K)	Ksv	Kq (×10¹²)	fa	n	K_a (×10⁶M^-1)	ΔG⁰ (kJ/mol)	ΔH⁰ (kJ/mol)	ΔS⁰ (J/mol^. K)
BSA/CDS-PMo₁₂@PVP₀	298	0.085	8.46	0.476	0.94	0.035	− 25.97	144.47	571.66
BSA/CDS-PMo₁₂@PVP₀	310	0.597	59.7	0.625	0.54	0.338	− 32.83	144.47	571.66
Hb/CDS-PMo₁₂@PVP₀	298	0.013	1.4	2.381	1.2	0.028	− 25.46	19.01	149.17
Hb/CDS-PMo₁₂@PVP₀	310	0.039	3.9	1.099	1.1	0.038	− 27.31	19.01	149.17
Cyt-C/CDS-PMo₁₂@PVP₀	298	0.045	4.52	1.449	1.3	0.04	− 26.31	22.14	162.5
Cyt-C/CDS-PMo₁₂@PVP₀	310	0.021	2.14	3.571	1.5	0.06	− 28.26	22.14	162.5
BSA/CDS-PMo₁₂@PVP₁	298	0.064	6.42	0.303	0.78	0.016	− 24.08	− 8.93	50.83
BSA/CDS-PMo₁₂@PVP₁	310	0.005	0.531	3.333	0.71	0.014	− 24.69	− 8.93	50.83
Hb/CDS-PMo₁₂@PVP₁	298	0.012	1.2	2.439	0.91	0.019	− 24.48	− 2.87	72.48
Hb/CDS-PMo₁₂@PVP₁	310	0.032	3.3	0.971	0.83	0.018	− 25.35	− 2.87	72.48
Cyt-C/CDS-PMo₁₂@PVP₁	298	0.004	4.04	4.545	0.98	0.032	− 25.74	− 7.35	61.67
Cyt-C/CDS-PMo₁₂@PVP₁	310	0.016	1.58	2.128	1.1	0.028	− 26.48	− 7.35	61.67

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