Fig. 6

Biodistribution and photothermal effect of the HTPR NPs in vivo. a In vivo fluorescence images of MNNG/HOS tumor-bearing mice at indicated time point after the intravenous injection with ICG labeled NPs (ICG@HTP and ICG@HTPR). b Ex vivo fluorescence images of tumor and main organs after 24 h of post-injection. c Semiquantitative analysis of fluorescence intensity in the tumors and major organs. d, e In vivo thermal images and temperature variation curves of tumor region recorded by using the NIR thermal camera during NIR laser irradiation (1.0 W cm⁻²)