Fig. 7

Evaluation of the synergistic therapeutic efficacy of formulations in vivo. a Schematic diagram of in vivo therapy in tumor-bearing mice. b Representative photographs of tumor-bearing mice after various treatments. c The photographs of all tumors taken from mice after various treatments. (Groups included (1) control, (2) PBS + NIR, (3) AIBI + NIR, (4) AHPR + NIR, (5) AHTPR + NIR). d Tumor volume growth curves of tumor-bearing mice during the administration of different formulations. e Tumor weights were measured after various treatments. f Body weight changes of MNNG/HOS tumor-bearing mice in different groups during the treatment. g H&E and immunohistochemical (TUNEL and Ki-67) analyses of tumor slices in different groups. (*P < 0.05, **P < 0.01, ***P < 0.001)