Fig. 1

Characterizations of M-CFN. A Characterization of M2 macrophages by flow cytometry examinations. B TEM images of CFN, scale bar, 50 nm. C TEM images of M-CFN, scale bar, 50 nm. D Particle size distribution of CFN and M-CFN measured by DLS analysis. E Protein profiles in CFN, macrophage membrane (MM), M-CFN and macrophages by electrophoresis assays. F Typical protein markers expressed in macrophages, microvesicles, MM, M-CFN and CFN by western-blot analysis. G EE values of CTX in CFN upon incubation in PBS (pH 7.4) and FBS. H EE values of CTX in M-CFN upon incubation in PBS (pH 7.4) and FBS