Fig. 2

In vitro cellular uptake and inhibition of tumorsphere formation. A Cellular uptake of CFN and M-CFN in parental 4T1 cancer cells, scale bar, 25 μm. B Cellular uptake of CFN and M-CFN in 4T1-induced tumorspheres, scale bar, 25 μm. C Quantified cellular uptake in 4T1 cancer cells, **p < 0.01. D Quantified cellular uptake in CSC-enriched tumorsphere cells, *p < 0.05. E Uptake of M-CFN and M-CFN + antiCD11b in 4T1-induced tumorsphere cells. F Cytotoxicity in CSCs-enriched tumorsphere cells. G Effects on inhibiting tumorsphere formation of 4T1 and MCF-7 cancer cells, scale bar, 200 μm