Fig. 7
In vivo therapeutic efficacy and eradication of ALDHhigh CSC fractions in tumors. A Tumor growth profiles from each group in 4T1 tumor models (n = 5). B Tumor weights from each group in 4T1 tumor models. C Effects on eradicating the ALDHhigh CSCs in 4T1 tumors, wherein the ALDHhigh CSCs were denoted as green fluorescence signals, scale bar, 50 μm. D Quantified effects on eradiating ALDHhigh CSCs in 4T1 tumors, **p < 0.01. E Average number of lung metastatic nodules from each group in 4T1 tumor models, **p < 0.01. F Histological examinations of lungs from each treatment in 4T1 tumor models, scale bar, 200 μm. The metastatic foci were denoted as cell clusters with darkly stained nuclei (red arrows). G Tumor growth profiles from each group in MCF-7 tumor models (n = 5). H Tumor weights from each group in MCF-7 tumor models, *p < 0.05, **p < 0.01. I Effects on eradicating the ALDHhigh CSCs in MCF-7 tumors, wherein the ALDHhigh CSCs are denoted as green fluorescence signals, scale bar, 50 μm. J Quantified effects on eradiating ALDHhigh CSCs in MCF-7 tumors, **p < 0.01