Fig. 1

Study design and characterization of Ang-EM. A Illustration of DTX@Ang-EM preparation, avoiding protein corona formation, escaping phagocytosis, BBB penetration and GBM targeting. B Size distribution and zeta potential of Lipo, Ang-Lipo and Ang-EM. C TEM images of Lipo, Ang-Lipo and Ang-EM. Scale bar = 100 nm. D Summary and comparison of mean size, polymey distribution index and zeta potential of Lipo, Ang-Lipo and Ang-EM. E SDS-page analysis of protein profiles of Ang-EM. MP, membrane proteins; Exo, Exosomes; cyto, cytosolic proteins. F Western blot of protein markers of CD63, CD9 and CD47 on EM and Exo