Fig. 7
A Thermal images and B temperature rise curves at tumor sites of 4T1 tumor-bearing mice after intravenous injection of saline or Au@Cu2-xSe NPs followed by NIR irradiation. C Body weight changes, D tumor volume growth curves, and E digital photographs of 4T1 tumor-bearing mice after intravenous injection of saline or Au@Cu2-xSe NPs followed by NIR irradiation. Data are presented as mean ± s.d. (n = 5). *P < 0.05, **P < 0.01, ***P < 0.001. F DCFH-DA, H&E, and TUNEL staining of tumor tissues after corresponding treatments, where blue represents the cell nucleus stained with DAPI. Scale bar = 50 μm. Saline: 200 µL. Au@Cu2-xSe: 2 mg mL−1 in saline, 200 µL. NIR: 808 nm laser, 1.0 or 1.5 W cm−2 for 5 min