Fig. 7

A Body weight alterations in the mice with SRNS during GC, H, GCH and Pm-GCH treatment. B Quantification of 24-h proteinuria after GC, H, GCH and Pm-GCH treatment. Representative images of kidneys after H&E staining (C) and Masson staining (D) after intravenous injection of (a) PBS, (b) GC, (c) H, (d) GCH and (e) Pm-GCH, respectively. Black arrows, enlarged Bowman’s space; green arrows, glomerular sclerosis. E The ultrastructure of the glomerular filtration barrier was assessed by transmission electron microscopy. fp foot process, GBM glomerular basement membrane