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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagy

Fig. 6

In vivo antitumor efficacy enabled by HHBP. a The tumor growth curves following different treatments (n = 3). ***P < 0.001. b Body weight of 4T1 tumor-bearing mice after different treatments (n = 3). c Representative images of the excised tumors after different treatments. (I) PBS, (II) HMME@HMONs-PEG, (III) HHBP, (IV) HMME@HMONs-PEG + US, and (V) HHBP + US. d Histological and immunohistochemical analyses of H&E, Ki67 and TUNEL assays for the excised tumor tissues after different treatments. Scale bar = 200 μm. e Representative immunofluorescence images of LC3 in the tumor tissues of mice after different treatments. Scale bar =100 μm

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Journal of Nanobiotechnology

ISSN: 1477-3155

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