Fig. 6

In vivo antitumor effect of subcutaneous inoculation of CT-26 cells in mouse model. a Tumor volume of mice in each treatment group changed. b Tumor growth-inhibition rate. c Excised tumor photographs. d Body weight change during treatment. e H&E staining and f Ki67 immunohistochemistry (arrow indicates positive proliferation), TUNEL staining (brown indicates apoptosis) of tumor tissue. Scale bar, 50 μm. Significance criteria: ^*P < 0.05, ^**P < 0.01, ^***P < 0.001