Table 1 Characterization of DTX-loaded liposomes
Formulation | Particle size (nm) | Zeta potential (mV) | Polydispersity index | EE (%) | DLC (%) | Number of conjugated RGD in per liposome | Number of conjugated Lf in per liposome |
|---|---|---|---|---|---|---|---|
PEG-LP-DTX | 90.89 ± 0.36 | −25.19 ± 0.89 | 0.208 | 71.17 ± 0.16 | 2.49 ± 0.01 | – | – |
RGD-LP-DTX | 103.6 ± 1.15 | −18.93 ± 1.01 | 0.213 | 73.49 ± 0.55 | 2.30 ± 0.02 | 105 | – |
Lf-LP-DTX | 119.7 ± 3.18 | −19.37 ± 1.70 | 0.206 | 75.34 ± 2.06 | 2.33 ± 0.13 | – | 28 |
RGD-Lf-LP-DTX | 135.8 ± 2.82 | −16.73 ± 0.42 | 0.219 | 78.42 ± 2.26 | 2.42 ± 0.01 | 105 | 28 |