Fig. 6

Design principle and therapeutic mechanism of Silicene@Silica-AQ4N. a Synthetic route of Silicene@Silica-AQ4N. b Illustration of the Silicene@Silica-AQ4N triggered synergistic photonic hyperthermia amplified chemotherapy in vivo. c The TEM, Dark-field TEM images, and corresponding elemental mapping of Silicene@Silica nanosheets. d Temperature change curves of Silicene@Silica-RGD under laser irradiation with different power densities. e The drug release of Silicene@Silica-AQ4N in PBS (pH = 7.4) under irradiated with laser irradiation with different power densities. f, g Cell viabilities of 4T1 cells treated by different conditions. h Temperature change curves at the tumor site of mice during different treatments. i Tumor volume of mice in different groups