Fig. 6
Biodistribution and in vivo MR/PA bimodal imaging of M@P-PDR. A Fluorescence images of 4T1 tumor-bearing mice at different time points (pre-injection, 1, 2, 4, 6, 8 and 24 h), and B the corresponding fluorescence intensities of tumors (n = 3). C In vivo PA images of tumors and E the corresponding signal intensities (n = 3). D T1-weighted MR images and F the corresponding PSIE of tumors (n = 3, t-test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)