Fig. 8

Mechanistic validation of BMSCs-derived exosome miR-7-5p-agomir against AML in vivo. A OSBPL11 (red) in the leukemic bone marrow tissues was analyzed by immunofluorescence staining after the mice were treated with different treatment modalities. Scale bar: 50 μm. B The animals were under the treatment of PBS, Exo-NC agomir and Exo-miR-7-5p agomir, respectively, and p-PI3K (green), p-AKT (yellow) and p-mTOR (pink) in the leukemic bone marrow tissues were analyzed by immunofluorescence staining. Scale bar: 50 μm