Fig. 8
Effect of the 3D hydrogel/nanofiber composite scaffolds on the angiogenesis in the wound beds. A Representative images of vessel network formation and immunofluorescent staining analysis of CD 31 expression at 7 and 11 days, respectively. (Green areas, CD31 positive cells indicating blood vessels; blue, nuclei stained with DAPI). Quantitative analysis of vessel network formation at C 7 days and D 11 days. Quantitative analysis of CD31-positive vessels per high-power field at E 7 days and F 11 days. Values are expressed as mean ± standard deviation (SD) (n = 3). (*P < 0.05, **P < 0.01, ***P < 0.001)