Fig. 5

In vivo antitumor and anti-metastasis evaluation. a Schematic of intravenous injection of nanoagonists into mice, laser treatment of primary tumors, and evaluation of therapeutic efficacy. Relative tumor volumes of primary tumors (b) and distant tumors (c) after intravenous injection of NA₀, NAc and dNAc into mice with or without NIR-II laser treatment (1 W/cm²) for 10 min. d H&E staining images of livers from mice after nanoagonist injection with or without NIR-II laser treatment (1 W/cm²) for 10 min. The white triangles indicated metastatic tumor nodules. e Quantification of liver metastasis of mice in different groups. f H&E staining images of lungs from mice. g Quantification of metastatic tumor nodules in lung of mice