Fig. 6
From: The bright future of nanotechnology in lymphatic system imaging and imaging-guided surgery
a, b The whole-body dynamic 3D-micro-magnetic resonance lymphangiography of mice injected with PAMAM-G8, DAB-G5, PAMAM-G4, Gadomer-17 and Gd-DTPA into foot gap. The MR images acquired at 10 and 45 min post-injection are shown, with permission from [95]. Copyright 2003, Wiley–VCH Verlag GmbH & Co. KGaA, Weinheim. c The magnetic resonance imaging and magnetic resonance angiography in rats. First two pictures: 3D-TOF-GRE hindlimb scan before (Native) and after (AGulX) intradermal AGuIX injection. Third: 3D-GRE angiography with intravenous Gadofosveset after AGuIX administrated 2 h. Last: Anatomical dissection after methylene blue injection. d Representative MRL images with AGuIX and Gd-DOTA in different time. The arrowhead shows the lymph nodes and collecting lymphatic vessels. Modified from [97]. Copyright 2017, Wolters Kluwer Health. e Comparison of CS015 and two commercially SPIOs for enhanced MR angiography with subcutaneous injection. f MR images of lymph nodes before and 24 h after intravenous injection of CS015. Reprinted with permission [103]. Copyright 2020, Elsevier