Fig. 1From: CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapyCharacterization of UCNPs-Cas9. TEM images of A NaYF4:Yb/Tm/Ca, B NaYF4:Yb/Tm/Ca@NaYF4:Yb/Nd. C XRD patterns of NaYF4:Yb/Tm/Ca@NaYF4:Yb/Nd. a.u., arbitrary units. D NaYF4:Yb/Tm/Ca@NaYF4:Yb/Nd and its EDX elemental mapping. E UV–vis absorption spectrum of UCNPs, UCNPs-PAA, Avidin and UCNPs-Avidin. F FTIR spectra of UCNPs, UCNPs-PAA and UCNPs-Avidin. G Fluorescence spectrum of UCNPs and UCNPs-PAA activated by 808 nm laser and UV–vis absorption spectrum of PCB. Inset: bright-field and NIR fluorescent images of UCNPsBack to article page