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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma

Fig. 2

BA NPs suppresses the proliferation of human U87 cells in vitro. A Cell viability measured by CCK8 assay after BA treatment with various concentrations (0, 3, 6, 12, 24, 48 µg/mL). B Cell viability measured by CCK8 assay after BA treatment with various times (0, 6, 12, 24, 36, 48, 72 h). C, F EDU assay shown that BA NPs inhibited DNA synthesis in U87 cells. *P < 0.05, **P < 0.01. D, E Cell cycle distribution analysis showing the G0/G1 arrest by flow cytometry of U87 cells after been treated with various concentrations (0, 5, 10, 15 µg/mL) BA NPs. *P < 0.05, **P < 0.01. G Western blot analysis of the expression of Cyclin D1

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