Fig. 5

Histological analysis and safety evaluation. a Digital photographs of liver, tumor ipsilateral inguinal lymph nodes and tumor tissues in PC3 tumor-bearing mice on day 19 post treatment. Scale bars, 10 mm. Representative H&E-stained images of liver tissue slices (b) and inguinal lymph nodes (c) on day 19 post treatment. d Quantification of hepatic metastatic nodules and tumor ipsilateral inguinal lymphatic metastatic nodules on day 19 post treatment. e H&E, TUNEL and Ki67 stained images of tumor tissue slices on day 19 post treatment. Scale bar, 100 μm. f Serum biochemical indexes of tumor-bearing mice on day 19 post treatment