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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Peptide-based semiconducting polymer nanoparticles for osteosarcoma-targeted NIR-II fluorescence/NIR-I photoacoustic dual-model imaging and photothermal/photodynamic therapies

Fig. 2

Photothermal and photodynamic performance of SPN-PT. A Photothermal conversion behavior of different concentrations of SPN-PT under laser irradiation (635 nm, 0.45 W cm−2). B IR thermal images of SPN-PT at concentrations corresponding to A irradiated by laser (635 nm, 0.45 W cm−2). Temperature elevation curves (C) and IR thermal images (D) of SPN-PT (100 µg ml−1) irradiated by different power densities of laser (635 nm, 0.05 W cm−2 - 0.60 W cm−2). E Temperature change curves of SPN-PT (100 µg mL−1) over 5 ON/OFF cycles employing 635 nm laser (0.5 W cm−2) followed by passive cooling every 5 min. F The photothermal heating and cooling curves of SPN-PT and PBS under the 635 nm laser irradiation (0.6 W cm−2). G Linear time data versus negative natural logarithm was obtained from the cooling period. Absorption spectra change of DPBF incubated with SPN-PT and irradiated by 635 nm laser at 0.5 W cm−2 (H) and 0.75 W cm−2 (I). J Absorption intensity changes of DPBF at 419 nm in the presence of SPN-PT (50 µg mL−1) with the irradiated time of 635 nm laser (0.5 W cm−2, red; 0.75 W cm−2, black)

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