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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: IR792-MCN@ZIF-8-PD-L1 siRNA drug delivery system enhances photothermal immunotherapy for triple-negative breast cancer under near-infrared laser irradiation

Fig. 4

Efficiency of IM@ZP under NIR laser irradiation in killing breast cancer cells in vitro. A Calcein AM/PI staining images of 4T1 cells incubated with PBS, IM@Z and IM@ZP with or without NIR laser irradiation (10 min, 1 W/cm2) for 12 h (green fluorescence indicates living cells, and red fluorescence indicates dead cells). B Viability of 4T1 cells incubated with PBS, IM@Z and IM@ZP with or without NIR laser irradiation (10 min, 1 W/cm2) for 12 h measured by CCK-8 assay. *p  < 0.05. C Flow cytometric analysis of cell apoptosis following incubation with PBS, IM@Z and IM@ZP with or without NIR laser irradiation (10 min, 1 W/cm2) for 12 h. *p  < 0.05

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