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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: IR792-MCN@ZIF-8-PD-L1 siRNA drug delivery system enhances photothermal immunotherapy for triple-negative breast cancer under near-infrared laser irradiation

Fig. 6

Promoted immune response by IM@ZP under NIR laser irradiation in vivo. A Flow cytometric analysis of CD4 +  and CD8 +  T cells in tumor tissues of mice treated with IM@Z, IM@Z  +  NIR, IM@ZP and IM@ZP  +  NIR. B Flow cytometric analysis of CD8  +  T cells in tumor tissues of mice treated with IM@Z, IM@Z  +  NIR, IM@ZP and IM@ZP  +  NIR. C Flow cytometric analysis of CD4 +  T cells in tumor tissues of mice treated with IM@Z, IM@Z  +  NIR, IM@ZP and IM@ZP  +  NIR. D Flow cytometric analysis of CD8  +  T cell proliferation in tumor tissues of mice treated with IM@Z, IM@Z  +  NIR, IM@ZP and IM@ZP  +  NIR. E Ki67-positive CD8  +  T cells in tumor tissues of mice treated with IM@Z, IM@Z  +  NIR, IM@ZP and IM@ZP  +  NIR. n  = 6 for mice following each treatment. *p  < 0.05

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