Fig. 4
From: Engineering of small-molecule lipidic prodrugs as novel nanomedicines for enhanced drug delivery
(Reprinted from Ref. [102] with permission. Copyright 2019, Elsevier Ltd)
Schematic illustration of prodrug nanoassemblies. The nanoparticles were self-assembled by PTX-S-OA, and PPa-PEG2k was performed for photodynamic PEG coating. Further, PTX-S-OA/PPa-PEG2k NPs were accumulated in the tumors, and self-enhanced core–shell synergistic therapy could be achieved after laser irradiation.