Fig. 5
From: Engineering of small-molecule lipidic prodrugs as novel nanomedicines for enhanced drug delivery
(Reprinted from Ref. [103] with permission. Copyright 2020, Elsevier Ltd)
PSPC nanoparticles constructed from SLPs for tumor-specific drug activation and combined chemo-photodynamic therapy. a Chemical structures of LTK-CTX and L-Ce6 prodrugs. b Self-assembly of the two prodrugs into nanoparticles. Upon light irradiation, the coassembled Ce6 generates ROS and triggers active drug release. c Schematic illustrating studies of the in vivo synergistic antitumor efficacy using the PSPC nanoassemblies.