Fig. 5
From: A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies
Correlation of the wRMSDi and in vitro binding abilities of Remicade and anti-TNF-α humanized candidates. The in silico simulated wRMSDi was linearly correlated with the logarithms of A the EC50 value of anti-TNF-α humanized candidates determined using ELISA (R2 = 0.9013) and B the KD anti-TNF-α humanized candidates determined using the BLItz affinity measurement system (R2 = 0.9921)