Fig. 7
In vivo anti-biofilm activity and wound healing evaluation. A, B Representative real-time thermal images of the mice treated with PBS and ICG-ZnS NPs irradiated with NIR (808 nm, 1 W cm−2). C Wound photograph of MRSA infected mice after treated with PBS, ICG-ZnS NPs and ICG-ZnS NPs + NIR for 0–7 days; Quantitative measurement of bacteria counts in wounds by standard plate count. D Quantitative analysis of relative wounds area over time. E Body weight changes during 7 days. F H&E staining images, Giemsa staining images, MT staining images and CD31 immunostaining images of skin tissues after treatments with PBS, ICG-ZnS NPs and ICG-ZnS NPs + NIR (scale bar: 200 μm). Data are presented as the means ± SD (n = 3), *P < 0.05, **P < 0.01