Fig. 5

The gel could prevent B16-F10 tumour recurrence after surgery. A In vivo bioluminescence imaging of B16-F10 tumour after primary tumour removal. Each treatment group showed four representative mice. The images related to day 10 were taken before the operation. B, C Average tumour growth kinetics in different groups. When the first mouse in the respective group died, the growth curve stopped. The data are expressed as mean ± SD (n = 6). Statistical significance is obtained through multiple comparisons between one-variance analysis and Tukey’s post-hoc test. D After the various treatments, the survival rate corresponded to the tumour size of the mice. The data are expressed as mean ± SD (n = 6). E Changes in body weight of mice in different groups. The data are expressed as mean ± SD (n = 4). F, H Tumours and spleens after different treatments (n = 5). Scale bars: 1 cm. G, I Quantitative graph of tumour and spleen weight. The data are expressed as mean ± SD (n = 5). G, I *P < 0.05; **P < 0.01; ****P < 0.0001