Skip to main content
Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Dental pulp stem cell-derived exosomes suppress M1 macrophage polarization through the ROS-MAPK-NFκB P65 signaling pathway after spinal cord injury

Fig. 7

DPSC derived exosomes can protect injured spinal cord. A At 28 days after injured spinal cord, NF200 and Neun are determined by immunofuorescence in different groups. NF200 and Neun are selected as biomarkers of neurons. B Histological images (H&E staining) of longitudinal sections of injured spinal cords. There were transitional regions between the undamaged area and the scar area in the PBS-treated group. There were no or very few neurons in the transitional regions. The transitional regions were smaller or less obvious in the exosome-treated group. C BMS scores at diferent time-point after spinal cord injury. At 28 days after SCI, the exosome-treated group had higher BMS scores. *p < 0.05, ***p < 0.01

Back to article page